Peggy’s search for the truth about Zero Matter puts her on a collision course with her superiors as Howard Stark barnstorms in.

With Simon being held captive at The Hotel DuMort, Clary pleads with Jace, Alec and Isabelle to help her rescue her best friend. As the team readies for the mission, Jace helps Clary learn more about her Shadowhunter powers, Isabelle turns to her favorite Seelie for Intel, and Alec begins to question Jace’s motives and his place in their partnership. Meanwhile, a very scared Simon gets very up close and personal with Camille, the leader of the vampire clan.

When Cisco gets a vibe of Eobard Thawne, Barry and the team don’t believe it. But, after an attack at Mercury Labs, Christina McGee confirms that the Reverse Flash is back. Meanwhile, Iris and Francine share a nice moment that brings Iris closer to her brother, Wally.

Will faces unforeseen challenges on his first day at his new job. Katie receives her first assignment. Maddie reconnects with an old acquaintance. Carlos pays the price for Will’s collaboration.

Three months have passed since the tragedy at Mount Weather and our heroes learn that a bounty has been put on Clarke’s head. Unbeknownst to Clarke, a team led by Bellamy and Kane journeys deep into Grounder territory to save her. Meanwhile, Murphy finds his way to the mansion and discovers a very different Jaha on a very different mission.

As the clock counts down to the end of the world, Tommy finds himself up against his biggest challenge yet as Erica takes drastic measures to see her plan succeed. Malina tries to fulfill her great-grandmother’s prophecy to save the world with the help of Luke and Quentin. Emily and Ren desperately search for Miko. Carlos is faced with a life and death choice.

In the year 2166, the immortal villain Vandal Savage is on the verge of his final victory – total chaos and the utter destruction of humanity. As the world crumbles, the Time Master Rip Hunter takes matters into his own hands; he travels 150 years into the past to assemble a carefully selected team of heroes and rogues to stop him. Hunter has chosen what seems like an ill-matched group: billionaire inventor Ray Palmer, who has created an exo-suit with the power to shrink him to miniscule size, as the Atom; Sara Lance, the White Canary, a trained assassin; Professor Martin Stein and Jefferson “Jax” Jackson, who together form the meta-human Firestorm; Leonard Snart, known as Captain Cold, and his partner Mick Rory, AKA Heat Wave, a pair of career criminals; and Kendra Saunders and Carter Hall AKA Hawkgirl and Hawkman. Together this unlikely group will attempt to stop one of the most formidable villains of all time, while they must learn how to not only be a team, but heroes as well.

Oliver must deal with the devastating consequences of Darhk’s last attack. Seeking revenge, Oliver goes on a brutal manhunt looking for Dahrk.

Brian embarks on his first FBI field assignment when he travels to Quantico to lend his skills to the bureau unit that catches serial killers. However, the trip takes a negative turn when Brian realizes the man he’s working with may have put away an innocent person in the career-making case that made him a renowned profiler. Also, Brian tries to stay one step ahead of Rebecca as she comes closer to discovering Senator Morra’s connection to NZT.

Peggy moves to the City of Angels to help Chief Daniel Sousa at the West Coast Strategic Scientific Reserve (SSR) investigate a bizarre homicide involving an alleged killer and Isodyne Energy, and reunites with some familiar faces.