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Vandal Savage arrives in Central City and sets his sights on Kendra Saunders. After Vandal attacks Kendra and Cisco, they turn to Barry for help. Realizing how dangerous Vandal is, Barry takes Kendra to Star City and asks Oliver and team to hide her until he can figure out how to stop Vandal. However, things quickly go from bad to worse when a man with wings AKA Hawkman shows up and flies off with Kendra. Meanwhile, Harrison develops a serum to make Barry run faster and asks Jay to test it out.

This cross-over episode concludes on Arrow's season 4 “Legends of Yesterday” episode.

The CIA and BND make a play.

Alicia and Lucca join forces with Louis Canning to defend a website accused of racial profiling. Meanwhile, Eli and Ruth worry about the nature of Alicia's relationship with Jason and how it could impact Peter's presidential campaign.

When Boyle’s former military buddy is accused of murder and blames it on the loss of control of his prosthetic arm, Boyle asks Brian to help determine if the artificial limb was hacked. Also, Brian’s father demands he stop working for the FBI.

Castle and Beckett investigate the murder of a cruise ship entertainer, only to find themselves trapped at sea with the killer.

Carrie needs Allison's help. Quinn's plans change.

Diane is personally conflicted when she is forced to argue a heated case between pro-choice and pro-life advocates in order to retain an important client, represented by attorney Ethan Carver. Also, Alicia and Lucca are desperate for new business and attempt to poach business from Louis Canning.

Jessica searches morgues for clues. Trish goes all-out to keep Simpson from getting in Jessica's way. Malcom has an epiphany.

The hunt for Kilgrave reunites Jessica with Luke. Trish receives some unexpected information about Simpson and Jessica.

Jessica and Luke get help from someone else in the neighborhood. Kilgrave gears up for a major test of powers against Jessica.