A patient at a mental hospital undergoes impromptu surgery that leaves his brain exposed. William Bell resurfaces during the investigation of the strange circumstances and Olivia finds reason that the leader of the shape-shifters may have something to do with it.
The Dunphy kids are in trouble again, but this time Claire and Phil are threatening to take Christmas away. Gloria and Manny want to incorporate some of their Colombian practices into Jay’s holiday traditions, but he wants to keep it his way. Meanwhile Cameron and Mitchell take Lily to the mall for her first picture with Santa, however this Santa isn’t very jolly.
Castle and Beckett uncover that a bullet is missing from the crime scene while investigating what happened when an art dealer was gunned down in his own gallery. However, when it turns out there was a witness to the murder, they need to refresh the man’s memory, only to find out that he suffers from amnesia and can’t even remember who he is.
When a perfect girl finally shows up, the gang tries everything to help Ted, while Marshall takes action when he discovers a letter written by younger himself.
The FBI investigates a spectacular jewelry heist and all the clues point to Neal. Now Peter must figure out if his « partner » is telling the truth or if Neal is pulling a con of his own.
Unexpected visitors greet H.R.G.; Samuel’s plan starts to come to fruition; struggling to accept the truth, Peter takes extreme measures to get what he wants; Claire’s journey leads her to an unexpected destination.
Despite being « banned-for-life, » Cal heads to Vegas when he is summoned by a casino owner after the star contender in the World Series of Poker goes missing right before the tournament. Meanwhile, Ria analyzes the expressions of the woman Eli is dating to determine if she’s « into him. »
Nothing is too big when Phil and Claire decide to throw Luke the biggest and best birthday party a boy could ever want, but when Cameron shows up as Fizbo the Clown, it sets off a chain of events that ends with someone in the hospital.
Frankie’s plan to have an idyllic family Thanksgiving backfires when Mr. Ehlert demands his staff work over the holiday. Brick goes missing in a corn maze.
Erica works with new allies to uncover a biological threat they suspect the Visitors have been plotting. Aboard the mothership, Anna meets with a special guest, while managing the investigation into the murder of a V. Chad does a segment on the V Healing Centers demonstrating their amazing medical abilities, but finds himself conflicted by some of his findings.