When a scientist falls dead after ingesting a lethal cloud of blue powder and his bones disintegrate in his body, the CDC suspects a biological attack. As the Fringe Team investigates further, a subject from Walter’s past with ties to Olivia reluctantly agrees to assist with the intense case.
Abed invites « Fat Neil » to play a game of Dungeons & Dragons with the rest of the study group, hoping to boost his confidence, after Jeff becomes concerned about him being a loner. When Pierce finds out he was not invited, he joins anyway, disrupting their plans.
When Alicia’s client confesses under duress to murdering a fellow prison inmate, Cary’s team seeks to challenge by uncovering an unlikely connection between the two inmates. Wendy threatens to expose a Florrick family issue in hopes of forcing Peter to drop out of the race.
After the radical faction of the Fifth Column murders three Peace Ambassadors, Erica goes on a mission to hunt down their leader, Eli Cohn, a former Mossad agent. Meanwhile, as Jack and other priests around the globe begin to speak out against the Visitors, Anna heads to the Vatican in an effort to convince the leaders of organized religion that the Visitors truly are « of peace. »
Annie convinces the group to put on a middle school anti-drug production, but finds it continually derailed by Pierce’s efforts to give himself a better role. Meanwhile, Chang attempts to connect with Shirley, while a prank involving Britta’s phone puts Jeff in an awkward situation.
When the detective who investigated Beckett’s mother’s murder is shot before Beckett’s eyes before he can give her new evidence in the case, Beckett’s old wounds are reopened. The investigation of the detective’s death leads the team to an old scheme which may provide the answer to why Beckett’s mother was murdered and who ordered it.
An Observer makes contact with the Fringe Team to help rectify a mistake. Meanwhile, Walter befriends Roscoe Joyce, keyboardist for Walter’s favorite 1970s band, « Violet Sedan Chair. » Walter will learn the real reason the band broke up, and realize that the lives of these two men, who have never met before, overlap in strange and unexpected ways.
The kids get a surprise of their own when they take breakfast in bed to Phil and Claire on their anniversary. Jay and Gloria’s Vegas vacation plans are ruined by a brutally honest email accidentally sent to Claire,. Mitchell and Cam try to get into a new restaurant owned by a mom at Lily’s preschool.
When Peter is suspended by the FBI for a crime he didn’t commit, he is forced to run a sting with Neal and the gang to catch Mozzie’s shooter, and clear his name.
Anna and Diana square off in the dark bowels of the Mothership – Diana has been down there for 15 years and not had a single glimpse of Anna. Meanwhile, Erica has Tyler’s blood analyzed, and learns the V’s did something sinister to her when she was pregnant with him.