Emerson is hired by Dusty Fitz, whose wife Kentucky died in a tragic bee-related incident. She was involved with another man who Dusty claims she was preparing to leave, and Dusty suspects murder. Meanwhile, Lily helps Olive move to a nunnery.
Jane orchestrates his own undercover operation using Van Pelt as bait as the team investigates the murder of a young waitress in the Napa Valley.
Broyles calls in the team to investigate a deadly explosion and its source: a strange cylinder unharmed despite the destruction. Olivia determines that the same cylinder, or a similar one, is responsible for similar events in widely diverse locations.
The entire operation may be in jeopardy when Mahone gets into trouble with the law. Gretchen’s sister receives a surprise visitor. The Company may be onto Self. T-Bag continues to raise suspicions at Gate.
HRG and his new partner go to a local bank heist with four villains; including Peter being trapped in one of them. Hiro and Ando track Daphne to Germany, and meet the Haitian. Tracy Strauss goes to New Orleans to find out more information about Niki. Meredith teaches Claire a lesson about fighting. Usutu shows Matt a series of paintings about him.
Marshall claims that he had the best hamburger in the world during his first week in New York City, but he forgot where the burger joint is located. The gang then hits the streets of Manhattan to help him find it.
When Daniel Jackson visits Atlantis, he and Dr. McKay discover a hidden lab that brings a new enemy knocking. The Daedalus welcomes a Wraith ally for a special project.
When Joy cons Make-A-Wish to send a celebrity to her trailer, Earl remembers a wish he stole from a dying child and decides it’s time to cross him off the list. When he returns to the kid’s home, he finds that little Buddy (guest star Seth Green) has exceeded all of the doctors’ expectations and is still alive. Buddy asks Earl to produce his movie and suddenly all of Camden County find themselves starring in a high-octane action film. Randy surprises everyone when his acting skills get rave reviews.
Earl and Randy decide it’s time to make amends with their childhood neighbors, the Clarks. But when they discover more skeletons in the closet than they had expected, the brothers find themselves needing to sort out some family issues between their mom and dad (Guest Star Beau Bridges). Meanwhile, Joy has duped one-eyed Willy out of his glass eye, and despite Darnell’s efforts Willy may never « see » that eye again.
This episode introduces us to the complex life of Patrick Jane, a police detective with a troubled past who has a keen eye for detail. When a man and woman are found dead in their home, many believe they are victims of a serial killer, but Patrick knows better and must prove that this was not the work of Red John.