Dale returns from trading with news that the Hudson River Virus has crossed the Mississippi River, and when the town’s vaccine supply is seized Jake coordinates a retrieval operation. Elsewhere, Hawkins is forced to show part of his hand to Beck.
Kyle begins having cognitive malfunctions and is drawing pictures in his sleep due to the attention demands from the other students during his midterm exams. Meanwhile, Kyle’s condition has Jessi creating her own tutoring service.
Walter and Skyler attend a former colleague’s birthday party. Jesse tries to free himself from drugs, while Skyler organizes an intervention.
As a mysterious new illness sweeps through the Pegasus Galaxy, Teyla is convinced by a vision that the father of her child is trying to communicate with her.
Jericho gets ready for a very important visitor from the new Cheyenne government. Meanwhile, Hawkins and Chavez work to find the new leaderships secrets.
LJ and Whistler are exchanged, but more surprises abound. Meanwhile, T-Bag’s scheming finally pays off.
Hoping to work things out with Jessi, Kyle takes her on a trip to research Sarah. Meanwhile, Lori and Hillary con Amanda into visiting a college bar in search of a DJ, and Andy and Josh seek couples counseling.
Walter finally tells his family that he has cancer. Meanwhile, the DEA believes Albuquerque has a new, big time player to worry about. Jesse makes a surprise visit to his parents home.
Teal’c visits Atlantis to counsel a headstrong Ronon, who is up for review by the I.O.A. But the two must work together when the Wraith invade the Midway space station in order to reach Earth.
Following the battle of New Bern, Jericho begins the rebuilding process, while the Cheyenne government shows a particular interest in the town. While the dispute between Jericho and New Bern is being sorted out by the Cheyenne government, Heather returns. Meanwhile, an old friend of Rob comes to Jericho.