As Danko spearheads the government operation, someone close to him is put in the line of fire. HRG’s life continues to spiral out of control and his marriage is dangerously close to the breaking point. Meanwhile, Hiro and Ando continue their road trip with a special delivery for Matt Parkman. Elsewhere, Angela Petrelli unearths the demons of her past.
As the day stretches into the middle of the night, Jack and the FBI formulate a plan to prevent further terror attacks. Events take an unexpected turn when the politics surrounding the administration expand beyond the White House.
Tensions and bills mount at the White household. Hank makes progress at work, but struggles with some residual effects from his encounter with Tuco. Jesse takes charge and assembles a crew of dealers to get their product out on the streets.
When Echo, Sierra and Victor awaken in the Dollhouse with most of their original personalities intact but no memories, Echo leads the charge to free the Actives from their apparent captivity and escape the Dollhouse forever. Meanwhile, Ballard discovers the Dollhouse is closer than he thinks.
Cal becomes obsessed when three young women from India commit suicide the same week. Meanwhile, Gillian and Eli help the SEC try to recover millions of dollars from a man accused of scamming his investors.
Patrick Jane and the CBI team track down a mastermind who hypnotizes people into doing their bidding.
The investigation behind a body found wrapped in a rug on the sidewalk leads Castle and Beckett deep inside the world of New York City politics. The partners discover a world of expensive escorts, arrogant tycoons, corrupt investigators, and the effects of betrayal.
When Barney learns Ted has a list of things he thinks the gang is too old to do, he sets out to do every task within 24 hours in order to prove Ted wrong.
Now that Nathan’s ability has been revealed and he has lost control of his operation, he and Claire go into hiding in Mexico. With Emile Danko now in control of the government operation, his plan to destroy everyone with abilities is set into motion as he teams up with an unlikely partner. Meanwhile, Angela and Peter seek refuge in a church and begin to mend their broken relationship.
The game changes for Jack Bauer, and the FBI is forced to collaborate with other federal agencies. As the threat intensifies, the administration shakes things up and seeks a new perspective.