Los Angeles Police Officer Matt Parkman is working crowd control at a murder scene when he alone begins to hear the muffled cries of a little girl somewhere in the house. Claire’s heroism brings her unwanted attention. Peter comes closer to learning the truth about his and Nathan’s powers. Hiro finds a comic book which leads him to Isaac.
Ted’s parents visit New York for their anniversary and he learns a family secret. Robin worries that they won’t like her. Lily and Marshall try to adjust to the new format of their relationship now that they are no longer together.
In order to help a friend Earl has to raise a lot of money. He goes to Richard Chubby (Burt Reynolds), owner of Club Chubby a local strip club. He agrees to loan Earl the money if Earl can convince his most popular dancer to come back and work for him.
S.A.R.A.H – the artificial intelligence that runs Carter’s house takes him and a group of residents hostage in an intervention to keep Carter in Eureka. Meanwhile her root program B.R.A.D activates and turns the situation deadly.
Mahone arrives in Salt Lake City, trying to locate exactly where in Utah the escapees are. Michael and Linc hatch a plan with T-Bag and Tweener that will enable them to dig in the right place. C-Note and Sucre meet on the highway and head toward Tooele. Kellerman, in Washington, D.C., briefs Kim. Governor Tancredi phones Sara with a warning.
In this episode, we are introduced to Peter Petrelli, a young man who dreams of flying, and his brother Nathan, a ruthless politician who thinks that Peter is dreaming his life away. Meanwhile, ordinary people from all around the world are starting to suspect that they have abilities beyond those of normal humans. Artist Isaac Mendez believes that he is painting the future, high school cheerleader Claire Bennet is suddenly able to recover from any wound almost instantly, Japanese businessman Hiro Nakamura tries to convince a friend that he can bend space and time, and single mother Niki Sanders starts seeing strange things in mirrors.Upon learning of his father’s death, genetics Professor Mohinder Suresh begins to look into his research for a clue to why he was killed. When he follows his father’s trail to New York City, however, Mohinder learns that someone else is on the trail of the same research. Someone who may kill to protect the secrets of the next step in human evolution.
Barney works with Marshall on his bachelor skills, which include hitting on women. Lily is back from her venture. Robin helps her look for a new apartment but gets sick of hearing about San Francisco.
The Atlantis expedition is stunned to learn that a ship full of Ancients is returning to reclaim their lost city.
SG-1 races against Baal in the hunt to find the Sangraal, Merlin’s anti-Ori weapon, and comes up against a series of ancient trials.
When Joy and Darnell get into an argument over her surprise birthday, Earl jumps at the opportunity to cross off number 183 on his list “Never took Joy’s side”. Meanwhile Joy runs into various problems after trying to return a television set she recently purchased.