Michael is three days behind on his plan to free his brother, particularly with his new insomniac cell mate, Haywire (Silas Weir Mitchell), whom he witnesses take some tablets to stay lucid, but escape when the doctors leave, describing them as « invisible handcuffs ». He then notices Michael’s tattoo and sees the hidden « maze » in it.

Meanwhile, Veronica Donovan (Robin Tunney) meets with Nick Savrinn (Frank Grillo) from « Project Justice », who wants to assist. They question Lincoln regarding the evidence, which he insists was planted. Sucre (Amaury Nolasco) is visited by his cousin, Hector Avila (Kurt Caceres), who tells him that Maricruz (Camille Guaty) is with him now. He eventually gets hold of Maricruz, and learns that Hector told her lies to get her not to come. With this new development, Sucre urges Michael to get him back into the cell.

Michael manages to get hold of two chemicals and uses them to corrode a pipe underneath the infirmary as part of the escape plan. He returns to his cell and notices Haywire has drawn his entire tattoo and ponders the pathway. Michael purposely injures himself to get the officers to take Haywire away before the plan is exposed. Sucre gets transferred back to Michael’s cell and continues the plan. Agent Kellerman (Paul Adelstein) suspects that Scofield may try to break Lincoln out and orders to transfer Scofield out the very next day.

Colonel Sheppard begins to undergo a disturbing physical transformation after being exposed to Beckett’s anti-Wraith drug.

Colonel Mitchell is injured in a skirmish with a warrior from a mythic tribe of rebel Jaffa, and is trained in their fighting techniques only so that he may engage in a ritual battle to the death.

A reporter is sent to Galactica to chronicle the harsh realities of life during wartime.

Tommy’s sister suddenly shows up in town when their dad is about to inherit a million dollars. Tommy and Janet decide to renew their wedding vows. Meanwhile, Mike is worried when he finds a lump.

Lincoln vows to make Abruzzi pay, but Scofield reminds him that Abruzzi is needed. Sucre is released from solitary and Scofield tests the former’s loyalty before revealing his plan. Sucre passes the test, but he decides to change his cell and stay out of trouble as he will be released soon. Abruzzi realizes that he must befriend Scofield in order to find Fibonacci. Bagwell plans to lynch Scofield. Abruzzi tries to reconcile with Scofield by having his men beat up Bagwell and thus the latter going to the solitary. Scofield tells Abruzzi about his plan and he agrees to cooperate. L.J.’s probation officer forces him to visit Lincoln and the father and son become closer after a long time. Before Barris can sign her testimony for Lincoln written by Donovan, Kellerman and his fellow agent, Hale, abduct and kill the former. Donovan decides to leave her fiance, Sebastian Balfour. Bellick brings Patoshik, a psychotic inmate, to Scofield’s cell. Patoshik becomes a problem for Scofield’s plan.

Tommy lays off the antidepressants when he is kicked off the hockey team. Sheila asks Tommy to talk Damien out of being a firefighter. Meanwhile, when Franco sees Laura with another guy he gets jealous and Tommy’s dad gets a surprise when he returns home from a three day trip to Atlantic City.

Michael Scofield is imprisoned in Fox River State Penitentiary. He finds his brother, Lincoln Burrows, who is a death row prisoner, and tells him that he is going to break them both out of the prison.

Michael Scofield and Fernando Sucre (Amaury Nolasco) face a lockdown in order for the guards to search cells for contraband, where they’re about to throw away a knife, but were stopped by Bellick (Wade Williams), who sends Sucre to SHU. Warden Pope (Stacy Keach) calls off the search for Michael’s cell, but Bellick feels determined to, and sneaks into his cell when the prisoners are away, and finds the name « Allen Schweitzer ». Bellick runs the name on the database, only to find no one matching it.

Meanwhile, Sucre urges Stolte to let him call Maricruz (Camille Guaty), but is refused. Veronica (Robin Tunney) investigates who is framing Lincoln Burrows. She finds a tape, where she sees Lincoln shoot Terrence Steadman dead. Lincoln claims that he is being framed, stating the man was already dead and Lincoln never pulled the trigger. She attempts to talk to Crab Simmonds (Tab Baker), who didn’t testify in his case, only to find out that he was killed of an apparent drug overdose. She is contacted by Leticia Barris (Adina Porter), Crab’s girlfriend, but as they meet, she is spooked as Kellerman (Paul Adelstein) and Hale (Danny McCarthy) are watching.

Back in Fox River, Michael attempts to get to a bolt from a bleacher belonging to T-Bag (Robert Knepper), but is stopped. He doesn’t want Scofield on the bleacher unless he will join in the racist battle between the whites and blacks, but he declines. On his second attempt, T-Bag’s gang take the bolt off him, so eventually, he decides to join in to get at the bolt. However, C-Note (Rockmond Dunbar) sees this, and when he confronts Scofield regarding the PUGNAc, he refuses to give the pills. Soon, everyone comes out of their cell for count, when the riot starts. Michael decides to get the bolt back from T-Bag’s cellmate (Brian Hamman), and does so after a struggle. C-Note sees this and stabs the cellmate several times; the wounded man dies in Michael’s arms. T-Bag believes Michael killed the cellmate, and plans to get ba

7 of the 4400 have died and Maia gets worse all the time Out of suspicion and despair Diana threatens Dr. Hudson with a gun. Lily has run away with Isabelle and Richard pleads he to come back. Marsdem seems unable to avoid a long prison term which makes Alison contact Kyle.