Someone puts his 4400 ability up for auction, and the Supreme Court will have a special session to determine if it’s legal and if the auction can continue. Diana and Tom are ordered to investigate. Meanwhile, pop diva Chloe Granger is at the 4400 Center and claims that Jordan’s book was a revelation to her. She even cut her tour short because she felt she needed to come to the 4400 Center and become a student. Jordan makes sure this new « recruit » is well treated as it will profit the center. Shawn is working on a recruitment video for the 4400 Center. Richard and Lily travel to Montana where they meet with Eric Papequash, who disappeared in 1955.

Gary Navarro, a minor league baseball player back after a 30-year absence, finds that hearing everyone’s unspoken thoughts is driving him to the edge of madness. When he seeks help from NTAC, the higher-ups are more interested in how he can unearth information about Jordan Collier than how they can assist Gary with getting his life back. As the case occupies the majority of his time, Tom finds himself struggling with his responsibilities as a single father. Meanwhile, Kyle starts to get his life back through the prospect of a new relationship, Diana finds herself dealing with the unexpected arrival of her younger sister April, and as Richard, Lily, and Isabelle continue their life on the run, Richard grows increasingly disturbed by his daughter’s apparent abilities.

It’s been one year since the 4400 returned. After a period of intense medical observation, Tom has returned to NTAC in a limited capacity, assigned only to desk duty. Diana, having been through a series of inept partners, finally finds a way to cut through the red tape and get Tom back, all while in the midst of formally adopting Maia. Meanwhile, Richard, Lily and the baby are still living in meager conditions in a mountain cabin far away from Jordan. Jordan has now closed Arcadia Estates, and is on the verge of opening « The 4400 Centers, » a place for non-members of the 4400 to discover « the 4400 within themselves. » Collier becomes Shawn’s guardian, and enlists him to heal important benefactors of the Centers.

It’s been one year since the 4400 returned. After a period of intense medical observation, Tom has returned to NTAC in a limited capacity, assigned only to desk duty. Diana, having been through a series of inept partners, finally finds a way to cut through the red tape and get Tom back, all while in the midst of formally adopting Maia. Meanwhile, Richard, Lily and the baby are still living in meager conditions in a mountain cabin far away from Jordan. Jordan has now closed Arcadia Estates, and is on the verge of opening « The 4400 Centers, » a place for non-members of the 4400 to discover « the 4400 within themselves. » Collier becomes Shawn’s guardian, and enlists him to heal important benefactors of the Centers.

Mandy uses Tony as leverage to try to force Michelle to aid in her escape.

A Chinese security operative captures and interrogates one of the CTU agents involved in the raid on the embassy.

Palmer and Logan argue over the option of evacuating all major cities that may be targets for the missile.

As the missile speeds toward its destination, Mandy cuts a deal with Jack and the President to give up Marwan’s location in exchange for a full pardon on all of her crimes.

Tony and Michelle share a happy reunion, but Jack finds his relationship with Audrey shattered as she makes her feelings known.

Logan’s advisor suggests a drastic course of action when the Chinese government demands that Jack be handed over to them for trial. Palmer tries desperately to warn Jack of the danger against him.

Jack’s life changes forever as Tony, Michelle and Chloe help him to evade the trap set for him by Secret Service.

Jack finds that his efforts to bargain with Marwan for the location of the missile strike are futile.

Heller pushes his son for information when CTU discovers that he may have had contact with Marwan before the attacks.

Logan finds himself in the middle of a power struggle between Palmer and the ambitious Speaker of the House.

Tony and Michelle explore their rekindled passion for each other, but their hopes for the future may be short-lived when a familiar player enters the game and takes a hostage.

CTU scrambles to forge an alibi when a Chinese representative produces evidence of American involvement in the raid on their embassy.

Audrey gives Jack the cold shoulder, while Palmer and Logan clash over the consequences of Palmer’s decisions.

Jack and Curtis close in on Marwan as the countdown for the missile launch moves ahead.

After Logan authorizes Palmer to take charge of the crisis, Palmer sanctions Jack and Curtis to infiltrate the Chinese Embassy on a covert operation to capture a suspect.

Tony and Michelle continue to bump into each other’s personal lives, while Buchanan expresses anger at being kept out of the mission.

Jack faces Audrey’s wrath when a medical dilemma places Paul’s life in jeopardy.

Chloe is unexpectedly thrust into fieldwork when a woman reports that her boyfriend may be part of the terrorist conspiracy.

Jack and Curtis find their latest efforts to trap Marwan thwarted by the Secret Service, who have orders to arrest Jack for insubordination.

Mike calls on ex-President David Palmer for help as Logan continues to display a lack of leadership.