Kane leads a mission to make peace with the Grounders. Meanwhile, Jasper agrees to participate in a risky experiment, Lincoln enters a world of pain and President Dante Wallace issues a warning. Finally, Finn’s search for Clarke takes a violent turn.
Phil is cooking Thanksgiving dinner this year with Luke as his sous chef, and Claire has no confidence in them and prepares a secret turkey of her own as backup. Meanwhile, Jay and Gloria had plans to spend the holiday away but when the trip gets canceled last minute, they decide not to tell anyone which quickly becomes the worst idea ever since the family dinner gets suddenly moved to their house and it turns into a mad scramble to cover their tracks. Mitch is tired of always being the bad cop so when Lily refuses to wear a nice dress to dinner, he forces Cameron to deal with it who then comes up with a very unconventional approach.
Oliver must stop an Arrow-obsessed serial killer, Carrie Cutter, who is convinced that The Arrow is her one true love and will stop at nothing to get his attention. Unfortunately, her way of getting his attention is to kill people. Meanwhile, Ray asks Felicity to be his date for a work dinner with important clients. Thea auditions new DJs for Verdant and meets Chase, a brash DJ with whom she immediately clashes.
With the Heck house in disarray due to the kitchen sink hole and miniature dining room table, Frankie suggests that the family enjoy a Thanksgiving feast at the local King’s Feast buffet. But all does not run so smoothly when Sue invites her boyfriend Darrin to dine with the family and gets the feeling that Mike doesn’t like him very much, Brick invites his quirky girlfriend Cindy, and Axl is forced by Frankie to invite a girl he doesn’t even know to the holiday meal.
Coulson and team find themselves in an epic face-off against Hydra to uncover an ancient secret, while Ward kidnaps his brother, Senator Christian Ward, for a violent trip down memory lane.
The Flash faces a new meta-human named Tony, who can turn himself into girded steel at will. While Dr. Wells and Caitlin are concerned about Barry’s safety, Cisco comes up with a plan to take Tony down. Meanwhile, Iris’s blog on The Flash gets her into trouble, and Eddie witnesses Tony’s abilities firsthand and begins to ask questions that Joe doesn’t want answered. Joe asks Dr. Wells to help him solve Nora Allen’s murder.
When Castle and Beckett learn that a murder victim may have been poisoned at an Old West-style resort, they visit the resort posing as newlyweds to uncover the truth.
Carrie organizes a last-ditch operation. Lockhart and Martha stall the ISI.
The Feds want Cary to work with them as they build a case against Lemond Bishop.
Peter presents Neal’s deal to his superiors at the FBI: Neal will bring down the Pink Panthers in exchange for his freedom. And this time Neal is making sure there are won’t be any technicalities. The stakes couldn’t be higher for Peter either, as Pillar makes it clear that the bureau is intent on bring down the Panthers and Peter could lose his job if Neal’s plan goes south. When Neal finds out that Keller is now part of the Panthers, Peter wants to call off the mission and simply take Keller down once and for all, but Neal knows that this is his last chance. He can’t trust Keller and can’t figure out why he didn’t sell him out to the Panthers right away, unless Keller needs something from him…