MacLeod's old compatriot Hugh Fitzcairn comes to town bearing a mystery — some of their other Immortal friends have disappeared suspiciously. MacLeod realizes that someone may be following Fitz, and realizes too late that Fitz has put Darius in danger by visiting him. Finding Darius dead in his chapel and Fitzcairn kidnaped, MacLeod won't rest until he finds the men responsible. Tracking the killers of his old friend, MacLeod discovers that there is a band of mortals hunting Immortals, and even holy ground is no protection from them. MacLeod finds the renegades in time to save Fitzcairn and confront James Horton, leader of the Hunters, but Horton eludes his grasp.

When the stepdaughter of an Immortal is raped, the Immortal comes after the young man. MacLeod, a guest in the home of the accused boy's father, feels he must protect the family from this unstoppable menace. He urges the Immortal to see due process done, but the man has no interest in listening to reason, and he lays siege to the house.

When fatal stabbing fails to kill him, Alfred Cahill becomes convinced that he has been chosen by a higher power to wage a crusade against 'perversion', and cuts a bloody path through Paris, murdering prostitutes and pimps, and endangering an old friend of Tessa's who has become a call girl. MacLeod tries to explain Immortality to Cahill, but he can't get through to him, and finally is forced to take his head.

Richie meets a beautiful young woman who leads him into the world of haute couture. His youthful jealousy causes him to run afoul of a world-class fashion designer, a deadly Immortal.

A day at the circus reunites MacLeod with a former lover, the Immortal femme-fatale, Amanda, who has always meant big trouble for him. Amanda, meanwhile, is in trouble of her own as her former partner, Blaine, has escaped from prison and wants her head. She plays the two Immortal men against each other, drawing MacLeod into a daring, high-stakes burglary she and Blaine are plotting.

Grace Chandel has been a Good Immortal, working for the betterment of mankind as a midwife, doctor, and scientist over the centuries. Her one weakness is another Immortal, Carlo Sendaro, a former lover who is obsessed with her and refuses to let her go. He slays Grace's current (mortal) lover and, when she refuses to run off with him, frames her for the killing. She turns to her old friend Duncan MacLeod for help.

A mysterious death at the Paris Opera re-acquaints Duncan MacLeod with one of the strangest Immortals he has met in his many travels over the centuries. Ursa is a hulking giant — more beast than man — who Duncan rescued from persecution centuries ago, delivering him to sanctuary in an abbey. The abbey has long since been destroyed and Ursa now lives under Paris. He has become enamored of a past-her-prime opera singer who tries to use Ursa's innocent soul to murder her rival.